Benzeneacetamide, α-chloro-
2-Chloro-2-phenylacetamide
CAS: 7462-76-2
Molecular Formula: C8H8ClNO
Benzeneacetamide, α-chloro- - Names and Identifiers
| Name | 2-Chloro-2-phenylacetamide |
| Synonyms | AURORA KA-7239 2-Chloro-2-phenylacetamide 2-CHLORO-2-PHENYLACETAMIDE Benzeneacetamide, α-chloro- 2-chloro-2-phenyl-ethanamide |
| CAS | 7462-76-2 |
Benzeneacetamide, α-chloro- - Physico-chemical Properties
| Molecular Formula | C8H8ClNO |
| Molar Mass | 169.61 |
| Sensitive | Irritant |
| MDL | MFCD06654371 |
Benzeneacetamide, α-chloro- - Introduction
2-Chloro-2-phenylacetamide (2-chloro-2-phenylacetamide) is an organic compound with the chemical formula C8H8ClNO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White or almost white crystal
-Solubility: Soluble in alcohols and ketones, slightly soluble in water
-melting point: about 91-93 ℃
-Refractive index: about 1.578(20 ℃)
Use:
2-Chloro-2-phenylacetamide is commonly used as a reagent and intermediate in organic synthesis. It can be used to synthesize other compounds, used in medicine, pesticides and other fields.
Preparation Method:
In general, the preparation of 2-Chloro-2-phenylacetamide can be carried out by the following reaction:
1. benzoic acid is reacted with sodium hypochlorite or potassium hypochlorite to generate benzoyl chloride.
2. Benzoyl chloride is reacted with ammonia water to obtain benzamide.
3. chlorination of benzamide to give 2-Chloro-2-phenylacetamide.
Safety Information:
The specific safety information of 2-Chloro-2-phenylacetamide needs to be checked according to relevant national regulations. Safety protection equipment such as lab gloves and goggles should be worn during operation. Avoid breathing gas or dust and avoid skin contact. In the event of an accident, immediately flush the affected area with plenty of water and seek medical help.
Nature:
-Appearance: White or almost white crystal
-Solubility: Soluble in alcohols and ketones, slightly soluble in water
-melting point: about 91-93 ℃
-Refractive index: about 1.578(20 ℃)
Use:
2-Chloro-2-phenylacetamide is commonly used as a reagent and intermediate in organic synthesis. It can be used to synthesize other compounds, used in medicine, pesticides and other fields.
Preparation Method:
In general, the preparation of 2-Chloro-2-phenylacetamide can be carried out by the following reaction:
1. benzoic acid is reacted with sodium hypochlorite or potassium hypochlorite to generate benzoyl chloride.
2. Benzoyl chloride is reacted with ammonia water to obtain benzamide.
3. chlorination of benzamide to give 2-Chloro-2-phenylacetamide.
Safety Information:
The specific safety information of 2-Chloro-2-phenylacetamide needs to be checked according to relevant national regulations. Safety protection equipment such as lab gloves and goggles should be worn during operation. Avoid breathing gas or dust and avoid skin contact. In the event of an accident, immediately flush the affected area with plenty of water and seek medical help.
Last Update：2024-04-09 15:18:09
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